Nuskin ArNOX – Scientific Review of ArNOX

Age-related NADH oxidase, or arNOX, is a previously unknown internal free radical generator found in the cell membranes of skin cells and whose activity increases as we age. This enzyme belongs to a class of newly discovered external NADH oxidase proteins that become increasingly active with age to generate additional metabolic energy, because cellular mitochondria age and therefore produce less energy.

As the arNOX enzyme generates superoxide free radicals on the cell surface, it damages adjacent cells and other components, such as collagen and elastin, causing the skin to sag and wrinkle. Unlike other free radicals produced by exposure to our environment, such as the sun or pollutants, it is our genes that control the activity of this arNOX enzyme, particularly during our “aging” years of 45 to 70 years. The higher our serum arNOX levels are, the older we look and the faster we age. In a clinical study conducted by Stanford University, clinical scientists concluded that study participants with the highest arNOX levels appeared on average seven years older, while participants with the lowest arNOX levels appeared on average seven years younger. . It is for this reason that some people naturally look younger for their age.

After making this discovery in 2008, scientists developed a technology called ageLOC, a proprietary blend of ingredients, which aims to slow the production of these skin-damaging free radicals at their source. This is achieved by blocking the arNOX enzyme, thus preventing the visible signs of aging before they appear.

The discovery of the arNOX enzyme is a revolutionary research breakthrough that now allows scientists to develop products that actually stop the signs of skin aging to complement the treatment of already damaged and aging skin.